Background: The aim of this study was to investigate and compare the prevalence of oral mucosal lesions in a group of psoriatic patients and healthy subjects.
Methods: 120 psoriatic patients were enrolled in this observational study. Clinical examination, panoramic X-ray, magnetic nuclear resonance of temporo-mandibular joint, parodontal evaluation, oropharyngeal buffer and incisional biopsies by scalpel, as applicable, were done in order to value the patients. The control group was formed by 201 non-psoriatic patients attending the hospital for dental conditions. Oral clinical evaluation of these patients was performed, to assess the presence of any oral manifestation that can be related to psoriasis: fissured tongue, geographic tongue, parodontitis, temporo-mandibular joint disorders and oral candidiasis. After the observational analysis, a statistical examination was conducted using the chi-square test (2-sided).
Results: A percentage of 78.34% of patients belonging to the case group presented oral manifestations, while in the control group the 35.3% of the individuals presented any oral lesions. Especially geographic and fissured tongue showed a strong correlation with psoriasis.
Conclusions: Some oral mucosal lesions, such as geographic and fissured tongue, are strongly associated with psoriasis. Although these lesions are non-pathognomonic to psoriasis, their precise relationship needs to be clarified and further investigated.