Could Ceramides Become the New Cholesterol?

Cell Metab. 2018 Feb 6;27(2):276-280. doi: 10.1016/j.cmet.2017.12.003. Epub 2018 Jan 4.


The Mayo Clinic recently introduced a diagnostic test that quantifies plasma ceramides in order to identify patients at risk of major adverse cardiac events. By comparing recent discoveries about these biomarker ceramides with the exhaustive body of literature surrounding cholesterol, Summers aims to highlight important advances and critically needed areas of investigation on this exciting class of bioactive lipids.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biomarkers / metabolism
  • Cardiovascular Diseases / metabolism
  • Ceramides / metabolism*
  • Cholesterol / metabolism*
  • Humans
  • Metabolic Diseases / metabolism


  • Biomarkers
  • Ceramides
  • Cholesterol