Visualization of the therapeutic efficacy of a gene correction approach in Wilson's disease by laser-ablation inductively coupled mass spectrometry

J Hepatol. 2018 May;68(5):1088-1090. doi: 10.1016/j.jhep.2017.12.022. Epub 2018 Jan 6.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Copper / metabolism
  • Copper-Transporting ATPases / deficiency
  • Copper-Transporting ATPases / genetics
  • Copper-Transporting ATPases / metabolism
  • Dependovirus / genetics
  • Hepatolenticular Degeneration / genetics*
  • Hepatolenticular Degeneration / metabolism
  • Hepatolenticular Degeneration / therapy*
  • Humans
  • Liver / metabolism
  • Male
  • Mass Spectrometry / methods
  • Mice
  • Mice, Knockout
  • Targeted Gene Repair / methods*

Substances

  • Copper
  • ATP7B protein, human
  • Atp7b protein, mouse
  • Copper-Transporting ATPases