Super-Resolution Microscopy in Studying the Structure and Function of the Cell Nucleus

S S Ryabichko; A N Ibragimov; L A Lebedeva; E N Kozlov; Y V Shidlovskii

Super-Resolution Microscopy in Studying the Structure and Function of the Cell Nucleus

Acta Naturae. 2017 Oct-Dec;9(4):42-51.

Authors

S S Ryabichko¹, A N Ibragimov¹, L A Lebedeva¹, E N Kozlov¹, Y V Shidlovskii^{1

2}

Affiliations

¹ Institute of Gene Biology RAS, Vavilova Str. 34/5, Moscow, 119334, Russia.
² I.M. Sechenov First Moscow State Medical University, Trubetskaya Str. 8, bldg. 2, Moscow, 119048 , Russia.

PMID: 29340216
PMCID: PMC5762827

Abstract

In recent decades, novel microscopic methods commonly referred to as super- resolution microscopy have been developed. These methods enable the visualization of a cell with a resolution of up to 10 nm. The application of these methods is of great interest in studying the structure and function of the cell nucleus. The review describes the main achievements in this field.

Keywords: DNA; cell nucleus; chromatin; chromosome; histone; super-resolution microscopy.