New Job for NK Cells: Architects of the Tumor Microenvironment

Immunity. 2018 Jan 16;48(1):9-11. doi: 10.1016/j.immuni.2018.01.001.


NK cells control tumor growth directly through targeted cytotoxic granule release or cytokine secretion and indirectly by orchestrating anti-tumor immune responses. In this issue of Immunity, Glasner et al. (2018) now reveal a new role for NK cells in preventing metastatic spread through controlling tumor architecture.

Publication types

  • Comment

MeSH terms

  • Cytoplasmic Granules
  • Humans
  • Killer Cells, Natural*
  • Neoplasms
  • Tumor Microenvironment*