MR-guided Focused Ultrasound for Uterine Fibroids: A Preliminary Study of Relationship between the Treatment Outcomes and Factors of MR Images Including Elastography

Shintaro Ichikawa; Utaroh Motosugi; Makiko Omori; Katsuhiro Sano; Yoshie Omiya; Shuji Hirata; Hiroshi Onishi

doi:10.2463/mrms.tn.2017-0103

MR-guided Focused Ultrasound for Uterine Fibroids: A Preliminary Study of Relationship between the Treatment Outcomes and Factors of MR Images Including Elastography

Magn Reson Med Sci. 2019 Jan 10;18(1):82-87. doi: 10.2463/mrms.tn.2017-0103. Epub 2018 Jan 18.

Authors

Shintaro Ichikawa¹, Utaroh Motosugi¹, Makiko Omori², Katsuhiro Sano³, Yoshie Omiya¹, Shuji Hirata², Hiroshi Onishi¹

Affiliations

¹ Department of Radiology, University of Yamanashi.
² Department of Obstetrics and Gynecology, University of Yamanashi.
³ Department of Diagnostic Radiology, Saitama International Medical Center, Saitama Medical University.

Abstract

We evaluated the value of magnetic resonance elastography (MRE) for the prediction of response to magnetic resonance-guided focused ultrasound (MRgFUS) for uterine fibroids. Eleven patients were enrolled. A fractional change of >30% in Symptoms Severity Score (SSS) was defined as a 'substantial symptomatic improvement' at 12 months after treatment. The fractional stiffness value reduction in the patients with a substantial improvement in SSS was significantly higher than that in those without (P = 0.0446).

Keywords: Symptoms Severity Score; magnetic resonance elastography; magnetic resonance-guided focused ultrasound; stiffness; uterine fibroid.

MeSH terms

Adult
Elasticity Imaging Techniques / methods*
Female
High-Intensity Focused Ultrasound Ablation / methods*
Humans
Leiomyoma* / diagnostic imaging
Leiomyoma* / surgery
Magnetic Resonance Imaging / methods*
Middle Aged
Retrospective Studies
Uterine Neoplasms* / diagnostic imaging
Uterine Neoplasms* / surgery