MR-guided Focused Ultrasound for Uterine Fibroids: A Preliminary Study of Relationship between the Treatment Outcomes and Factors of MR Images Including Elastography

Magn Reson Med Sci. 2019 Jan 10;18(1):82-87. doi: 10.2463/ Epub 2018 Jan 18.


We evaluated the value of magnetic resonance elastography (MRE) for the prediction of response to magnetic resonance-guided focused ultrasound (MRgFUS) for uterine fibroids. Eleven patients were enrolled. A fractional change of >30% in Symptoms Severity Score (SSS) was defined as a 'substantial symptomatic improvement' at 12 months after treatment. The fractional stiffness value reduction in the patients with a substantial improvement in SSS was significantly higher than that in those without (P = 0.0446).

Keywords: Symptoms Severity Score; magnetic resonance elastography; magnetic resonance-guided focused ultrasound; stiffness; uterine fibroid.

MeSH terms

  • Adult
  • Elasticity Imaging Techniques / methods*
  • Female
  • High-Intensity Focused Ultrasound Ablation / methods*
  • Humans
  • Leiomyoma* / diagnostic imaging
  • Leiomyoma* / surgery
  • Magnetic Resonance Imaging / methods*
  • Middle Aged
  • Retrospective Studies
  • Uterine Neoplasms* / diagnostic imaging
  • Uterine Neoplasms* / surgery