Glimmers in illuminating the druggable genome

Nat Rev Drug Discov. 2018 May;17(5):301-302. doi: 10.1038/nrd.2017.252. Epub 2018 Jan 19.


Much biomedical research continues to focus on a small proportion of the human genome that has already been studied intensively. The Illuminating the Druggable Genome programme, initiated as a pilot project by the US National Institutes of Health Common Fund in 2014, is now being implemented to accelerate the investigation of subsets of understudied proteins that have potential therapeutic relevance.

MeSH terms

  • Biomedical Research
  • Genome, Human / genetics*
  • Humans
  • National Institutes of Health (U.S.)
  • Pilot Projects
  • Proteins / genetics
  • United States


  • Proteins