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Published Erratum
. 2018 Feb 5;150(2):369.
doi: 10.1085/jgp.20171188901162018c. Epub 2018 Jan 22.

Correction: The relationship between form and function throughout the history of excitation-contraction coupling

Published Erratum

Correction: The relationship between form and function throughout the history of excitation-contraction coupling

Clara Franzini-Armstrong. J Gen Physiol. .
No abstract available

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Figures

Figure 9.
Figure 9.
RYR3 in a parajunctional position are necessary for the production of sparks in zebrafish muscle. (A) Triad in a 72 h postfertilization larva. Two sets of feet (RYR1) connect SR to the central T tubule profile. Additional feet profiles in a parajunctional position (arrowheads) have been proposed to be RYR3 (Felder and Franzini-Armstrong, 2002). (B) One-cell-stage embryos were injected with a morpholino designed to specifically silence RYR3 expression. In triads of larvae at 72 h postfertilization, RYR1 position was normal, but parajunctional feet were essentially missing. (C) The Ca2+ sparks frequency in WT and morpholino-injected (MO) embryos dropped in correspondence to the absence of parajunctional feet. Reprinted from Perni et al. (2015).

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