Bilateral Versus Single Internal Thoracic Artery Grafts

Curr Cardiol Rep. 2018 Jan 23;20(1):4. doi: 10.1007/s11886-018-0947-1.

Abstract

Purpose of review: Several advances have been made in recent years to improve outcome for patients with coronary artery disease. One of the most debated topics regarding surgical treatment with coronary artery bypass grafting (CABG) is graft selection. This review aims to present the current status and scientific evidence for bilateral internal thoracic artery (BITA) grafting.

Recent findings: Observational studies and pooled analyses suggest that BITA grafting is associated with improved survival. Early results from a large randomized controlled trial report safety and efficacy of the method. The improved survival might be amplified in select groups, but with an increase in sternal wound-related complications. The benefit of BITA grafts seems to remain to an approximate age of 69 years at surgery. CABG with BITA grafts is likely associated with improved long-term survival at a cost of an increase in sternal wound infections. Ten-year results from the Arterial Revascularization Trial are expected in 2018, providing the best evidence regarding the method yet. Early results show it is a safe method in most patient categories considerable for CABG.

Keywords: Arterial grafting; BITA; CABG; Internal thoracic artery; Long-term survival; Sternal wound infections.

Publication types

  • Review

MeSH terms

  • Coronary Artery Bypass / methods*
  • Coronary Artery Disease / mortality*
  • Coronary Artery Disease / surgery*
  • Humans
  • Mammary Arteries / transplantation*
  • Observational Studies as Topic
  • Randomized Controlled Trials as Topic
  • Risk Factors
  • Time Factors
  • Treatment Outcome