Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 26, e20170146

Psychopathological Profile and Quality of Life of Patients With Oral Lichen Planus


Psychopathological Profile and Quality of Life of Patients With Oral Lichen Planus

Małgorzata Radwan-Oczko et al. J Appl Oral Sci.


Oral lichen planus (OLP) is a chronic, multifocal, sometimes painful, inflammatory disease of the oral mucosa. OLP can predispose development of psycho-emotional disorders. Until now, the relationship between the severity of lichen planus and the psychological profile of patients (psychological well-being, perceived stress and pain coping strategies) has never been studied. Study was conducted on 42 OLP patients. Number of sites involved, severity and activity score of OLP were evaluated. Psychological tests were used to evaluate patients' psycho-emotional condition. The mean duration time of symptomatic OLP was 43 months. We detected that the longer the duration of subjective symptoms, the poorer the quality of life and the higher the level of perceived stress (PSS). Also, the higher the PSS results, the greater the anxiety and depression on Hospital Anxiety and Depression Scale (HADS). Likewise, higher level of depression in HADS was strongly correlated with worse quality of life. (p≤0.05). In this study, we detected a relationship between duration of the disease, level of perceived stress and quality of life. The longer the disease lasts, the higher it tends to catastrophize. This may influence development or increase of the anxiety and depression and may decrease patients' quality of life.

Conflict of interest statement

Conflict of interests

The authors declare no conflict of interests regarding the publication of this study.

Similar articles

See all similar articles

Cited by 3 PubMed Central articles


    1. Carrozzo M, Scally K. Oral manifestations of hepatitis C virus infection. World J Gastroenterol. 2014;20(24):7534–7543. - PMC - PubMed
    1. Chaudhary S. Psychosocial stressors in oral lichen planus. Aust Dent J. 2004;49(4):192–195. - PubMed
    1. Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983;24(4):385–396. - PubMed
    1. Dupuy HJ. The Psychological general Well-Being Index (PGWBI) In: Wenger NK, Mattson ME, Furberg CD, Elinson J, editors. Assessment of Quality of Life in clinical trials of cardiovascular therapies. New York: Le Jacq Publishing; 1984. pp. 170–183.
    1. Eisen D. The clinical features, malignant potential, and systemic associations of oral lichen planus: a study of 723 patients. J Am Acad Dermatol. 2002;46(2):207–214. - PubMed

MeSH terms