Wrinkle and roughness measurement by the Antera 3D and its application for evaluation of cosmetic products

Skin Res Technol. 2018 Aug;24(3):359-366. doi: 10.1111/srt.12436. Epub 2018 Jan 24.


Background: Skin topographic measurements are of paramount importance in the field of dermo-cosmetic evaluation. The aim of this study was to investigate how the Antera 3D, a multi-purpose handheld camera, correlates with other topographic techniques and changes in skin topography following the use of a cosmetic product.

Methods: Skin topographic measurements were collected on 26 female volunteers aged 45-70 years with the Antera 3D, the DermaTOP and image analysis on parallel-polarized pictures. Different filters for analysis from the Antera 3D were investigated for repeatability, correlations with other imaging techniques and ability to detect improvements of skin topography following application of a serum.

Results: Most of Antera 3D parameters were found to be strongly correlated with the DermaTOP parameters. No association was found between the Antera 3D parameters and measurements on parallel-polarized photographs. The measurements repeatability was comparable among the different filters for analysis, with the exception of wrinkle max depth and roughness Rt. Following a single application of a tightening serum, both Antera 3D wrinkles and texture parameters were able to record significant improvements, with the best improvements observed with the large filter.

Conclusion: The Antera 3D demonstrated its relevance for cosmetic product evaluation. We also provide recommendations for the analysis based on our findings.

Keywords: Antera; fringe projection; roughness; skin imaging; texture; wrinkle.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Cosmetics / pharmacology*
  • Female
  • Humans
  • Imaging, Three-Dimensional
  • Middle Aged
  • Photography
  • Skin / diagnostic imaging*
  • Skin / drug effects
  • Skin Aging / drug effects*


  • Cosmetics