The incidental thyroid nodule

CA Cancer J Clin. 2018 Mar;68(2):97-105. doi: 10.3322/caac.21447. Epub 2018 Jan 25.

Abstract

Incidental thyroid nodules that are found on an imaging study performed for reasons other than thyroid pathology represent a common scenario encountered by health care providers. The initial workup for these nodules comprises a thorough history and physical examination, thyroid function tests, a dedicated thyroid ultrasound, and fine-needle aspiration of any suspicious lesions. Management ranges from observation and reassurance to surgical resection and depends on the cytologic diagnosis. In cases of cytologically indeterminate or discordant nodules, surgical excision (lobectomy) offers a definitive diagnosis, although molecular testing or a reasonable period of observation may be useful as less invasive adjuncts. CA Cancer J Clin 2018;68:97-105. © 2018 American Cancer Society.

Keywords: endocrine neoplasm; incidental findings; thyroid neoplasm; thyroid nodule.

Publication types

  • Review

MeSH terms

  • Biopsy, Fine-Needle
  • Diagnosis, Differential
  • Humans
  • Incidental Findings
  • Molecular Diagnostic Techniques
  • Positron-Emission Tomography / methods
  • Practice Guidelines as Topic
  • Thyroid Function Tests
  • Thyroid Neoplasms / diagnosis*
  • Thyroid Neoplasms / pathology
  • Thyroid Neoplasms / surgery*
  • Thyroid Nodule / diagnosis*
  • Thyroid Nodule / pathology
  • Thyroid Nodule / surgery
  • Ultrasonography / methods