Head First, Not Feet First: Freeman-Sheldon Syndrome as Primarily a Craniofacial Condition

Cleft Palate Craniofac J. 2018 May;55(5):787-788. doi: 10.1177/1055665617753482. Epub 2018 Jan 25.


The historical and clinical basis for classification of Freeman-Sheldon syndrome as a craniofacial syndrome and explanation of the rationale underlying this decision is provided. Correctly classifying the condition will avoid confusion and may help to clarify the vernacular employed and eventually aid in improving diagnosis.

Keywords: anatomy; craniofacial growth; craniofacial morphology; dental anomalies; dysmorphology; facial growth; facial morphology; genetics; midfacial growth; muscle function.

Publication types

  • Letter

MeSH terms

  • Craniofacial Dysostosis / classification*
  • Humans
  • Maxillofacial Development

Supplementary concepts

  • Freeman-Sheldon syndrome