Cortical gamma oscillations in isolated dystonia

Svjetlana Miocinovic; Nicole C Swann; Coralie de Hemptinne; Andrew Miller; Jill L Ostrem; Philip A Starr

doi:10.1016/j.parkreldis.2018.01.017

Cortical gamma oscillations in isolated dystonia

Parkinsonism Relat Disord. 2018 Apr:49:104-105. doi: 10.1016/j.parkreldis.2018.01.017. Epub 2018 Jan 20.

Authors

Svjetlana Miocinovic¹, Nicole C Swann², Coralie de Hemptinne³, Andrew Miller⁴, Jill L Ostrem⁵, Philip A Starr⁶

Affiliations

¹ Department of Neurology, Emory University, Atlanta, GA, USA. Electronic address: Svjetlana.miocinovic@emory.edu.
² Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA. Electronic address: Nicole.Swann@ucsf.edu.
³ Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA. Electronic address: Coralie.Dehemptinne@ucsf.edu.
⁴ Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA. Electronic address: Andew.Miller@ucsf.edu.
⁵ Department of Neurology, University of California San Francisco, San Francisco, CA, USA. Electronic address: Jill.Ostrem@ucsf.edu.
⁶ Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA. Electronic address: Philip.Starr@ucsf.edu.

PMID: 29371063
DOI: 10.1016/j.parkreldis.2018.01.017

Abstract

We describe a novel electrophysiologic signal from the motor cortex of patients with generalized dystonia - a discrete gamma-band oscillation induced by movement and associated with emergence of dystonia. This was observed using both invasive and non-invasive methods. This phenomenon is similar to the gamma oscillation reported in parkinsonian dyskinesia.

Keywords: Cortex; Electrophysiology; Motor network; Oscillations.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Dystonic Disorders / physiopathology*
Electrocorticography
Female
Gamma Rhythm / physiology*
Humans
Male
Motor Cortex / physiopathology*
Young Adult