Cryptococcal meningitis in a daily cannabis smoker without evidence of immunodeficiency

BMJ Case Rep. 2018 Jan 26;2018:bcr2017221435. doi: 10.1136/bcr-2017-221435.


Cryptococcal meningitis is a life-threatening condition most commonly observed in immunocompromised individuals. We describe a daily cannabis smoker without evidence of immunodeficiency presenting with confirmed Cryptococcus neoformans meningitis. An investigation of cannabis samples from the patient's preferred dispensary demonstrated contamination with several varieties of Cryptococcus, including C. neoformans, and other opportunistic fungi. These findings raise concern regarding the safety of dispensary-grade cannabis, even in immunocompetent users.

Keywords: disease and health outcomes; drugs misuse (including addiction); exposures; healthcare improvement and patient safety; infectious diseases.

Publication types

  • Case Reports

MeSH terms

  • Cryptococcus neoformans*
  • Female
  • Humans
  • Marijuana Smoking / adverse effects*
  • Meningitis, Cryptococcal / microbiology*
  • Middle Aged