Fulminant hemolysis in glucose-6-phosphate dehydrogenase deficiency

Clin Case Rep. 2017 Nov 24;6(1):224-225. doi: 10.1002/ccr3.1290. eCollection 2018 Jan.

Abstract

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked disorder affecting some 400 million people worldwide. Though clinically silent, it may result in hemolysis on oxidative stress induced by drugs or infections. Viral hepatitis A with coexisting G6PD deficiency can be devastating associated with severe hemolysis, anemia, renal failure, and hepatic encephalopathy.

Keywords: Glucose‐6‐phosphate dehydrogenase deficiency; X‐linked inherited disorder; hemolysis; viral hepatitis.