HyperArc VMAT planning for single and multiple brain metastases stereotactic radiosurgery: a new treatment planning approach

Radiat Oncol. 2018 Jan 29;13(1):13. doi: 10.1186/s13014-017-0948-z.


Purpose: The HyperArc VMAT (HA-VMAT) planning approach was newly developed to fulfill the demands of dose delivery for brain metastases stereotactic radiosurgery. We compared the dosimetric parameters of the HA-VMAT plan with those of the conventional VMAT (C-VMAT).

Material and methods: For 23 patients (1-4 brain metastases), C-VMAT and HA-VMAT plans with a prescription dose of 20-24 Gy were retrospectively generated, and dosimetric parameters for PTV (homogeneity index, HI; conformity index, CI; gradient index, GI) and brain tissue (V2Gy-V16Gy) were evaluated. Subsequently, the physical characteristics (modulation complexity score for VMAT, MCSV; Monitor unit, MU) of both treatment approaches were compared.

Results: HA-VMAT provided higher HI (1.41 ± 0.07 vs. 1.24 ± 0.07, p < 0.01), CI (0.93 ± 0.02 vs. 0.90 ± 0.05, p = 0.01) and lower GI (3.06 ± 0.42 vs. 3.91 ± 0.55, p < 0.01) values. Moderate-to-low dose spreads (V4Gy-V16Gy) were significantly reduced (p < 0.01) in the HA-VMAT plan over that of C-VMAT. HA-VMAT plans resulted in more complex MLC patterns (lower MCSV, p < 0.01) and higher MU (p < 0.01).

Conclusions: HA-VMAT plans provided significantly higher conformity and rapid dose falloff with respect to the C-VMAT plans.

Keywords: Brain metastases; Dosimetric parameter; HyperArc; Stereotactic radiosurgery; VMAT.

MeSH terms

  • Adult
  • Aged
  • Brain Neoplasms / radiotherapy*
  • Brain Neoplasms / secondary
  • Female
  • Humans
  • Male
  • Middle Aged
  • Radiosurgery / methods*
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted / methods*
  • Radiotherapy, Intensity-Modulated / methods*
  • Retrospective Studies
  • Young Adult