A case study of Ramsay Hunt Syndrome in conjunction with cranial polyneuritis

Medicine (Baltimore). 2017 Nov;96(47):e8833. doi: 10.1097/MD.0000000000008833.


Rationale: Ramsay Hunt syndrome in conjunction with cranial polyneuritis is not extensively documented, and is very easily misdiagnosed.

Patient concerns: A case of a 53-year-old male with Ramsay Hunt syndrome in conjunction with cranial polyneuritis is presented with early symptoms of vertigo, cephalalgia, and facial palsy, followed by zoster oticus 10 days later.

Diagnoses: Diagnosis was challenging as this condition presents with multiple neuropathies, and attempting to diagnose based on clinical symptoms was often misleading. Polymerase chain reaction can be used to test for presence of the virus in the cerebrospinal fluid, followed by targeted drug therapy.

Interventions: Acupuncture, in conjunction with fire cupping, bloodletting around the afflicted region on the face, as well as oral consumption of herbal medicine and vitamins for nerve nourishment was given to treat this disease.

Outcomes: Due to misdiagnosis resulting in delayed treatment, peripheral facial paralysis was left as the main sequelae, while other symptoms responded quickly to treatment. After a 6-month follow-up, facial palsy was still present.

Lessons: Considering that targeted antiviral therapy can be used to increase the effectiveness of treatment, early diagnosis, and timely use of medication is critical.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / therapeutic use
  • Cranial Nerve Diseases / diagnosis*
  • Cranial Nerve Diseases / virology
  • Diagnostic Errors / adverse effects*
  • Facial Paralysis / diagnosis
  • Facial Paralysis / virology
  • Headache / diagnosis
  • Headache / virology
  • Herpes Zoster Oticus / diagnosis*
  • Herpes Zoster Oticus / virology
  • Humans
  • Male
  • Middle Aged
  • Neuritis / diagnosis*
  • Neuritis / virology
  • Vertigo / diagnosis
  • Vertigo / virology


  • Antiviral Agents