The First Case of Trypanosoma cruzi-Associated Retinitis in an Immunocompromised Host Diagnosed With Pan-Organism Polymerase Chain Reaction

Christopher D Conrady; Kimberly E Hanson; Sonia Mehra; Adrienne Carey; Marissa Larochelle; Akbar Shakoor

doi:10.1093/cid/ciy058

The First Case of Trypanosoma cruzi-Associated Retinitis in an Immunocompromised Host Diagnosed With Pan-Organism Polymerase Chain Reaction

Clin Infect Dis. 2018 Jun 18;67(1):141-143. doi: 10.1093/cid/ciy058.

Authors

Christopher D Conrady¹, Kimberly E Hanson², Sonia Mehra³, Adrienne Carey², Marissa Larochelle¹, Akbar Shakoor¹

Affiliations

¹ Department of Ophthalmology, John A. Moran Eye Center, University of Utah, Salt Lake City.
² Department of Medicine, Division of Adult Infectious Diseases, University of Utah, Salt Lake City.
³ Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City.

PMID: 29385482
DOI: 10.1093/cid/ciy058

Abstract

We report the first case of Trypanosoma cruzi-associated retinitis diagnosed using 28s ribosomal DNA sequencing. The case highlights the utility of broad-range molecular diagnostics for detecting rare and unsuspected ocular pathogens. Ocular involvement in Chagas disease is also discussed.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Chagas Disease / complications*
Chagas Disease / diagnosis*
DNA, Protozoan / genetics
DNA, Ribosomal / genetics
Humans
Immunocompromised Host*
Male
Molecular Diagnostic Techniques
Multiple Myeloma / complications
Polymerase Chain Reaction
Retinitis / diagnosis
Retinitis / parasitology*
Sequence Analysis, DNA
Trypanosoma cruzi / isolation & purification*

Substances

DNA, Protozoan
DNA, Ribosomal