Metal stents placement for refractory pancreatic duct stricture in children

World J Gastroenterol. 2018 Jan 21;24(3):408-414. doi: 10.3748/wjg.v24.i3.408.

Abstract

Aim: To evaluate the use of fully covered self-expandable metal stents (FCSEMSs) for pancreatic duct strictures in children with chronic pancreatitis.

Methods: Eight patients with refractory benign dominant stricture of the main pancreatic duct (MPD) were enrolled through chart reviews between December 2014 and June 2017 in a single center. Endoscopic retrograde cholangiopancreatography (ERCP) with placement of a 6-mm FCSEMS with dual flaps was performed. Endoscopic removal of FCSEMSs was performed with a snare or rat-tooth forceps. All procedures were performed by a pediatric gastroenterologist. For the assessment of outcomes, technical and clinical success, adverse events, and stent patency were evaluated retrospectively.

Results: The placement and removal of the FCSEMSs were successful in all 8 patients. Five patients were boys and 3 were girls. The median age at initial FCSEMS placement was 12 years (range, 5-18 years). The diameters of all the inserted stents were 6 mm, and the lengths were 4-7 cm. The median indwelling time was 6 mo (range, 3-10 mo). No pancreatic sepsis, pancreatitis, cholestasis, or mortality occurred. There was no proximal and distal migration. All subjects showed a patent stent. On follow-up ERCP, the mean diameter of the stricture improved from 1.1 mm to 2.8 mm (P < 0.05), whereas that of upstream dilation improved from 8.4 mm to 6.3 mm (P < 0.05).

Conclusion: This initial experience showed that temporary FCSEMS placement is feasible and safe for the management of refractory benign MPD stricture in children.

Keywords: Child; Chronic pancreatitis; Endoscopic retrograde cholangiopancreatography; Pancreatic duct; Self-expandable metal stent.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Cholangiopancreatography, Endoscopic Retrograde
  • Constriction, Pathologic / diagnostic imaging
  • Constriction, Pathologic / etiology
  • Constriction, Pathologic / surgery
  • Device Removal / adverse effects
  • Device Removal / instrumentation
  • Device Removal / methods
  • Dilatation / adverse effects
  • Dilatation / instrumentation*
  • Dilatation / methods
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Pancreatic Ducts / diagnostic imaging
  • Pancreatic Ducts / pathology*
  • Pancreatic Ducts / surgery
  • Pancreatitis, Chronic / complications
  • Pancreatitis, Chronic / diagnostic imaging
  • Pancreatitis, Chronic / pathology
  • Pancreatitis, Chronic / surgery*
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Self Expandable Metallic Stents / adverse effects*
  • Treatment Outcome