1 Section of Pediatric Critical Care Medicine, Children's Hospital of Orange County and David Geffen School of Medicine at the University of California, Los Angeles, CA Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, MA Cardiothoracic Intensive Care Unit, National University Health System, Singapore; and Paediatric Intensive Care Unit, Department of Paediatrics, The Royal Children's Hospital, University of Melbourne, Parkville, VIC, Australia.