A 79-year-old woman presented with a chief complaint of a palpated tumor on her right axilla. The right breast tumor size was 18mm and the axillary lymph node size was 30 mm, as detected with ultrasonography. Pathological findings indicated the presence of an ER(-), Pg R(-), HER2-negative apocrine carcinoma. The presence of axillary lymph node metastasis was diagnosed from the apocrine carcinoma. Eribulin(1.5mg)was administered 3 times before surgery. Tumors were significantly reduced. The Bt+Ax(Patey procedure)dissection was performed until Level 2. The pathological findings of the tumor revealed coagulation, necrosis, and the remaininglimited cancer lesions in the periphery zone. No remainingcancer cells were detected in the lymph nodes. The breast apocrine carcinoma was determined as a special type of invasive cancer. Although the prognosis is positive, the current case was considered highly malignant with a 50% positive Ki-67 rating. Although eribulin was effective, it seems that this case requires strict follow-up observations.