Compliance to timely vaccination in an Expanded Program on Immunization center of Pakistan

Vaccine. 2019 Jul 26;37(32):4618-4622. doi: 10.1016/j.vaccine.2018.01.044. Epub 2018 Feb 1.


The importance of childhood immunization in prevention of highly fatal diseases and disability cannot be overemphasized. Pakistan has a national Expanded Program on Immunization but the compliance is far below the international benchmark for achieving a herd immunity. Monitoring the compliance to timely receipt of vaccinations is crucial to establishing and preventing disease and disability associated risk in children. There is little or no evidence that reports the timeliness of the vaccinations according to the EPI schedule in Peshawar. The primary objective of the study was to evaluate rate of Fully Immunized Children and to report compliance to the timeliness of vaccine specific schedule during the study period in the EPI center in the capital city of Peshawar, Khyber Pakhtunkhwa province of Pakistan. We collected consecutive retrospective data of the infants enrolled from June 2014 to December 2015 in one EPI center for our study. Out of the total 157 (n) children, fully immunized children (FIC) were 62 (39.5%) and only 19 (12.1%) were FIC with timely visits. Dropouts increased with successive vaccinations with highest for Measles 1 (42%). On-time vaccinations decreased over time, while the proportion of children receiving vaccination outside the ideal window period reaches as high as 46%. The study reports a low compliance to EPI schedule, and also highlights that immunization coverage is not a good indicator of age appropriate vaccinations.

Keywords: Expanded program on immunization; Pakistan; Vaccination coverage; Vaccination timeliness.

MeSH terms

  • Cross-Sectional Studies
  • Female
  • Humans
  • Immunization Programs*
  • Immunization Schedule*
  • Infant
  • Infant, Newborn
  • Male
  • Pakistan
  • Patient Compliance / statistics & numerical data*
  • Time Factors
  • Vaccination Coverage / statistics & numerical data*