Current state and recommendations for harmonization of serum/plasma 17-hydroxyprogesterone mass spectrometry methods

Ronda F Greaves; Chung Shun Ho; Tze Ping Loh; Jia Hui Chai; Lisa Jolly; Peter Graham; Michaela F Hartmann; Yolanda B de Rijke; Stefan A Wudy; Working Group 3 “Harmonisation of Laboratory Assessment” European Cooperation in Science and Technology (COST) Action BM1303 “DSDnet”

doi:10.1515/cclm-2017-1039

Current state and recommendations for harmonization of serum/plasma 17-hydroxyprogesterone mass spectrometry methods

Clin Chem Lab Med. 2018 Sep 25;56(10):1685-1697. doi: 10.1515/cclm-2017-1039.

Affiliations

¹ School of Health and Biomedical Sciences, RMIT University, PO Box 71, Bundoora, Melbourne, Victoria, 3083 Australia.
² Centre for Hormone Research, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
³ Biomedical Mass Spectrometry Unit, Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, Peoples Republic of China.
⁴ Department of Laboratory Medicine, National University Hospital, Singapore, Singapore.
⁵ RCPA Quality Assurance Programs Chemical Pathology, Sydney, New South Wales, Australia.
⁶ Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics in Pediatric Endocrinology, Justus Liebig University, Giessen, Germany.
⁷ Department of Clinical Chemistry, Erasmus MC, Rotterdam, Netherlands.

PMID: 29397022
DOI: 10.1515/cclm-2017-1039

No abstract available

Keywords: 17-hydroxyprogesterone; congenital adrenal hyperplasia; disorders of sex development; harmonization; hormone; mass spectrometry; reference intervals; steroid.

MeSH terms

17-alpha-Hydroxyprogesterone / blood
17-alpha-Hydroxyprogesterone / standards*
Adolescent
Adult
Child
Chromatography, High Pressure Liquid / standards
Cross-Sectional Studies
Female
Humans
Male
Mass Spectrometry / standards*
Pre-Analytical Phase / standards
Quality Control

Substances

17-alpha-Hydroxyprogesterone