Severe Sympathomimetic Toxidrome in a French Soldier: How Caffeine Overdose Can Lead to Severe Consequences

Mil Med. 2018 Jan 1;183(1-2):e179-e181. doi: 10.1093/milmed/usx062.

Abstract

We report the case of a French soldier, 29-yr-old, hospitalized in intensive care unit at Begin Military Hospital for the management of a sympathomimetic syndrome associated with severe metabolic disorders. Diagnosis of voluntary caffeine overdose was made. The evolution was favorable after metabolic disorders correction, without the need for dialysis. Caffeine is a molecule free of serious adverse effects when consumed at low doses. However, when consumed at high doses, it can become toxic and lead to death. Caffeine consumption has increased in recent years and especially in French Army. This toxicity remains unknown by a large part of population. We must be vigilant because this substance misuse can lead to serious consequences.

Keywords: caffeine intoxication; metabolic acidosis; suicide; sympathomimetic toxidrome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Adult
  • Caffeine / adverse effects*
  • Caffeine / toxicity*
  • Central Nervous System Stimulants / adverse effects
  • Central Nervous System Stimulants / toxicity
  • Drug Overdose / diagnosis*
  • Fluid Therapy / methods
  • France
  • Humans
  • Male
  • Military Personnel*
  • Sweating
  • Sympathomimetics / adverse effects
  • Sympathomimetics / pharmacokinetics*
  • Tachycardia / etiology
  • Tremor / etiology
  • Vomiting / etiology

Substances

  • Central Nervous System Stimulants
  • Sympathomimetics
  • Caffeine