The Upper Esophageal Sphincter Assist Device Is Associated With Symptom Response in Reflux-Associated Laryngeal Symptoms

Clin Gastroenterol Hepatol. 2018 Oct;16(10):1670-1672. doi: 10.1016/j.cgh.2018.01.031. Epub 2018 Jan 31.

Abstract

Reflux-associated laryngeal symptoms (RALS) is the process in which chronic laryngeal symptoms are related to gastroesophagopharyngeal reflux.1 Impairment of upper esophageal sphincter (UES) reflexes may predispose to esophagopharyngeal reflux.1 The novel noninvasive nonpharmacologic UES assist device (UESAD) applies external cricoid pressure to augment intraluminal UES pressure by 20 to 30 mm Hg and reduce esophagopharyngeal reflux events.2 This study aimed to assess the therapeutic efficacy of the UESAD in a pragmatic clinical setting, and to identify factors associated with symptom response among patients with suspected RALS.

Trial registration: ClinicalTrials.gov NCT02552966.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Equipment and Supplies*
  • Esophageal Sphincter, Upper / physiopathology*
  • Female
  • Gastroesophageal Reflux / complications*
  • Gastroesophageal Reflux / therapy*
  • Humans
  • Laryngeal Diseases / epidemiology*
  • Laryngeal Diseases / etiology*
  • Male
  • Middle Aged
  • Prospective Studies
  • Treatment Outcome

Associated data

  • ClinicalTrials.gov/NCT02552966