Extradural petromastoid calcifying pseudoneoplasm of the neuraxis (CAPNON): Case report and literature review

Clin Neurol Neurosurg. 2018 Mar:166:99-106. doi: 10.1016/j.clineuro.2018.01.010. Epub 2018 Jan 12.


Background: Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a very rare tumor with fewer than 70 cases reported in the literature. In general, this tumor occurs intracranially either within the brain parenchyma or in an extra-axial location, but it has also been described within the spine as an extra-axial lesion.

Case description: We describe an unusual case of intracranial-extradural CAPNON involving the mastoid region. This may be only the second such case reported in the literature, as one patient with CAPNON has been reported involving the sinonasal region. Our patient was managed with surgical resection through a translabyrinthine approach with good early result.

Conclusions: We describe an unusual case of extradural CAPNON involving the mastoid bone. It appears that when located extradurally, this tumor may have a predilection for the bony sinuses. This little-known, generally benign entity can mimic more common lesions such as meningiomas, and should be considered in the differential diagnosis of skull base tumors, particularly when associated with heavy calcification.

Keywords: Calcification; Calcifying pseudoneoplasm of neuraxis; Intracranial-extradural; Petromastoid; Skull base tumors.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Calcinosis / diagnostic imaging*
  • Calcinosis / surgery
  • Female
  • Humans
  • Mastoid / diagnostic imaging*
  • Mastoid / surgery
  • Skull Base Neoplasms / diagnostic imaging*
  • Skull Base Neoplasms / surgery
  • Spinal Canal / diagnostic imaging
  • Spinal Canal / surgery