Nutritional Interventions in the Patient with Inflammatory Bowel Disease

Gastroenterol Clin North Am. 2018 Mar;47(1):155-177. doi: 10.1016/j.gtc.2017.09.007. Epub 2017 Dec 7.


Nutritional strategies have been explored as primary or adjunct therapies for inflammatory bowel disease (IBD). Exclusive enteral nutrition is effective for the induction of remission in Crohn disease and is recommended as a first-line therapy for children. Dietary strategies focus on adjusting the ratio of consumed nutrients that are proinflammatory or antiinflammatory. Treatments with dietary supplements focus on the antiinflammatory effects of the individual supplements (eg, curcumin, omega-3 fatty acids, vitamin D) or their positive effects on the intestinal microbiome (eg, prebiotics, probiotics). This article discusses the role of diets and dietary supplements in the treatment of IBD.

Keywords: Clinical remission; Crohn’s disease; Diet; Dietary supplements; Microbiome; Prebiotics; Probiotics; Ulcerative colitis.

Publication types

  • Review

MeSH terms

  • Colitis, Ulcerative / therapy*
  • Crohn Disease / therapy*
  • Curcumin / therapeutic use
  • Diet*
  • Diet, Gluten-Free
  • Dietary Fiber / administration & dosage
  • Dietary Sugars / administration & dosage*
  • Dietary Supplements*
  • Enteral Nutrition
  • Fatty Acids, Omega-3 / therapeutic use
  • Glutamine / therapeutic use
  • Humans
  • Immunoglobulin G / blood
  • Parenteral Nutrition
  • Prebiotics
  • Probiotics / therapeutic use
  • Vitamin D / therapeutic use


  • Dietary Fiber
  • Dietary Sugars
  • Fatty Acids, Omega-3
  • Immunoglobulin G
  • Prebiotics
  • Glutamine
  • Vitamin D
  • Curcumin