Approaching the Roundabout: cis and trans Robo1 Contacts Revealed

Structure. 2018 Feb 6;26(2):183-184. doi: 10.1016/j.str.2018.01.012.


In this issue of Structure,Aleksandrova et al. (2018) present low- and high-resolution structures of Robo1, a key player in axonal guidance. The structures shed light on the arrangement of Robo1 at the plasma membrane and provide evidence for back-to-back trans Robo1 contacts.

Publication types

  • Comment

MeSH terms

  • Nerve Tissue Proteins / chemistry*
  • Receptors, Immunologic / chemistry*


  • Nerve Tissue Proteins
  • Receptors, Immunologic