Mealtime Is NONO Speckled: Timing Hepatic Adaptation to Food

Cell Metab. 2018 Feb 6;27(2):268-270. doi: 10.1016/j.cmet.2018.01.009.


You are what you eat; but when you eat also seems to be important for a healthy metabolism. In this issue of Cell Metabolism, Benegiamo et al. (2018) uncover a mechanism by which the RNA-binding protein NONO promotes the time-of-day-dependent expression of key metabolic genes at a post-transcriptional level in response to nutrition.

Publication types

  • Comment

MeSH terms

  • Nuclear Matrix-Associated Proteins*
  • Octamer Transcription Factors*
  • RNA-Binding Proteins


  • Nuclear Matrix-Associated Proteins
  • Octamer Transcription Factors
  • RNA-Binding Proteins