The Magistral Phage

Viruses. 2018 Feb 6;10(2):64. doi: 10.3390/v10020064.


Since time immemorial, phages-the viral parasites of bacteria-have been protecting Earth's biosphere against bacterial overgrowth. Today, phages could help address the antibiotic resistance crisis that affects all of society. The greatest hurdle to the introduction of phage therapy in Western medicine is the lack of an appropriate legal and regulatory framework. Belgium is now implementing a pragmatic phage therapy framework that centers on the magistral preparation (compounding pharmacy in the US) of tailor-made phage medicines.

Keywords: antibiotic; antimicrobial resistance; compounding pharmacy; magistral preparation; personalized medicine; phage therapy; regulatory framework.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / therapeutic use
  • Bacteriophages / physiology*
  • Belgium
  • Drug Discovery
  • Drug Industry
  • Health Policy
  • Humans
  • Phage Therapy* / economics
  • Phage Therapy* / methods
  • Phage Therapy* / standards


  • Anti-Infective Agents