Raising concerns about the Sepsis-3 definitions

World J Emerg Surg. 2018 Jan 25:13:6. doi: 10.1186/s13017-018-0165-6. eCollection 2018.


The Global Alliance for Infections in Surgery appreciates the great effort of the task force who derived and validated the Sepsis-3 definitions and considers the new definitions an important step forward in the evolution of our understanding of sepsis. Nevertheless, more than a year after their publication, we have a few concerns regarding the use of the Sepsis-3 definitions.

Keywords: Infections; Organ dysfunction; Sepsis; Septic shock.

Publication types

  • Review

MeSH terms

  • Arterial Pressure
  • Consensus
  • Data Accuracy*
  • Glasgow Coma Scale
  • Humans
  • Organ Dysfunction Scores
  • Sensitivity and Specificity
  • Sepsis / classification*
  • Sepsis / mortality
  • Severity of Illness Index*