Screening for Chlamydia trachomatis and Neisseria gonorrhoeae Infections in Men Who Have Sex With Men: Diagnostic Accuracy of Nucleic Acid Amplification Test on Pooled Urine, Anorectal, and Pharyngeal Specimens

Sex Transm Dis. 2018 Mar;45(3):195-198. doi: 10.1097/OLQ.0000000000000722.

Abstract

Neisseria gonorrhoeae and Chlamydia trachomatis screening was performed in a cohort of 100 men who have sex with men. A nucleic acid amplification test on a pooled sample of first-pass urine, pharyngeal, and anorectal specimens was compared with results on nonpooled samples. Despite an excellent agreement (Cohen κ, 0.932), pooling specimens reduced test sensitivity to 89.5%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Chlamydia Infections / diagnosis*
  • Chlamydia Infections / microbiology
  • Chlamydia trachomatis / genetics
  • Chlamydia trachomatis / isolation & purification
  • Data Accuracy
  • Gonorrhea / diagnosis*
  • Gonorrhea / microbiology
  • Homosexuality, Male
  • Humans
  • Male
  • Mass Screening
  • Middle Aged
  • Neisseria gonorrhoeae / genetics
  • Neisseria gonorrhoeae / isolation & purification
  • Nucleic Acid Amplification Techniques
  • Pharyngeal Diseases / diagnosis*
  • Pharyngeal Diseases / microbiology
  • Pharynx / microbiology
  • Rectal Diseases / diagnosis*
  • Rectal Diseases / microbiology
  • Sensitivity and Specificity
  • Sexual and Gender Minorities / statistics & numerical data*
  • Young Adult