Industry-corrupted psychiatric trials

Psychiatr Pol. 2017 Dec 30;51(6):993-1008. doi: 10.12740/PP/80136. Epub 2017 Dec 30.
[Article in English, Polish]


The goal of this paper is to expose the research misconduct of pharmaceutical industry sponsored clinical trials via three short case studies of corrupted psychiatric trials that were conducted in the United States. We discuss the common elements that enable the misrepresentation of clinical trial results including ghostwriting for medical journals, the role of key opinion leaders as co-conspirators with the pharmaceutical industry and the complicity of top medical journals in failing to uphold standards of science and peer review. We conclude that the corruption of industry-sponsored clinical trials is one of the major obstacles facing evidence-based medicine.

Keywords: ghostwriting; key opinion leaders; pharmaceutical industry.

Publication types

  • Review

MeSH terms

  • Biomedical Research / trends*
  • Clinical Trials as Topic / standards*
  • Drug Industry*
  • Humans
  • Peer Review, Research
  • Research Support as Topic / trends*
  • United States