The cost of Alzheimer's disease in China and re-estimation of costs worldwide

Jianping Jia; Cuibai Wei; Shuoqi Chen; Fangyu Li; Yi Tang; Wei Qin; Lina Zhao; Hongmei Jin; Hui Xu; Fen Wang; Aihong Zhou; Xiumei Zuo; Liyong Wu; Ying Han; Yue Han; Liyuan Huang; Qi Wang; Dan Li; Changbiao Chu; Lu Shi; Min Gong; Yifeng Du; Jiewen Zhang; Junjian Zhang; Chunkui Zhou; Jihui Lv; Yang Lv; Haiqun Xie; Yong Ji; Fang Li; Enyan Yu; Benyan Luo; Yanjiang Wang; Shanshan Yang; Qiumin Qu; Qihao Guo; Furu Liang; Jintao Zhang; Lan Tan; Lu Shen; Kunnan Zhang; Jinbiao Zhang; Dantao Peng; Muni Tang; Peiyuan Lv; Boyan Fang; Lan Chu; Longfei Jia; Serge Gauthier

doi:10.1016/j.jalz.2017.12.006

The cost of Alzheimer's disease in China and re-estimation of costs worldwide

Alzheimers Dement. 2018 Apr;14(4):483-491. doi: 10.1016/j.jalz.2017.12.006. Epub 2018 Feb 9.

Authors

Jianping Jia¹, Cuibai Wei², Shuoqi Chen³, Fangyu Li³, Yi Tang³, Wei Qin³, Lina Zhao³, Hongmei Jin³, Hui Xu³, Fen Wang³, Aihong Zhou³, Xiumei Zuo³, Liyong Wu³, Ying Han³, Yue Han³, Liyuan Huang³, Qi Wang³, Dan Li³, Changbiao Chu³, Lu Shi³, Min Gong³, Yifeng Du⁴, Jiewen Zhang⁵, Junjian Zhang⁶, Chunkui Zhou⁷, Jihui Lv⁸, Yang Lv⁹, Haiqun Xie¹⁰, Yong Ji¹¹, Fang Li¹², Enyan Yu¹³, Benyan Luo¹⁴, Yanjiang Wang¹⁵, Shanshan Yang¹⁶, Qiumin Qu¹⁷, Qihao Guo¹⁸, Furu Liang¹⁹, Jintao Zhang²⁰, Lan Tan²¹, Lu Shen²², Kunnan Zhang²³, Jinbiao Zhang²⁴, Dantao Peng²⁵, Muni Tang²⁶, Peiyuan Lv²⁷, Boyan Fang²⁸, Lan Chu²⁹, Longfei Jia³⁰, Serge Gauthier³¹

Affiliations

¹ Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, China; Beijing Key Laboratory of Geriatric Cognitive Disorders, Beijing, China; Center of Alzheimer's Disease, Beijing Institute for Brain Disorders, Beijing, China; Key Laboratory of Neurodegenerative Diseases, Ministry of Education, Beijing, China; National Clinical Research Center for Geriatric Disorders, Beijing, China. Electronic address: jjp@ccmu.edu.cn.
² Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, China. Electronic address: chuibainews@126.com.
³ Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, China.
⁴ Department of Neurology, Shandong Provincial Hospital, Shandong University, Jinan, China.
⁵ Department of Neurology, Henan Provincial People's Hospital, Zhengzhou, China.
⁶ Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan, China.
⁷ Department of Neurology, The First Teaching Hospital of Jilin University, Changchun, China.
⁸ Dementia Unit, Beijing Geriatric Hospital, Beijing, China.
⁹ Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
¹⁰ Department of Neurology, Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, China.
¹¹ Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.
¹² Department of Gerontology, Fuxing Hospital, Capital Medical University, Beijing, China.
¹³ Department of Psychiatry, Zhejiang Provincial People's Hospital, Hangzhou, China.
¹⁴ Department of Neurology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China.
¹⁵ Department of Neurology, Daping Hospital, Third Military Medical University, Chongqing, China.
¹⁶ Department of Neurology, Daqing Oilfield General Hospital, Daqing, China.
¹⁷ Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
¹⁸ Department of Neurology and Institute of Neurology, Huashan Hospital Fudan University, Shanghai, China.
¹⁹ Department of Neurology, Baotou Central Hospital, Baotou, China.
²⁰ Department of Neurology, The 88th Hospital of PLA, Taian, China.
²¹ Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, China.
²² Department of Neurology, Xiangya Hospital Central South University, Changsha, China.
²³ Department of Neurology, People's Hospital of Jiangxi Province, Nanchang, China.
²⁴ Department of Neurology, Weihai Municipal Hospital, Weihai, China.
²⁵ Department of Neurology, Center for Geriatric Medicine, China-Japan Friendship Hospital, Beijing, China.
²⁶ Department of Geriatric Psychiatric, Guangzhou Huiai Hospital, Guangzhou, China.
²⁷ Department of Neurology, Hebei General Hospital, Shijiazhuang, China.
²⁸ Department of Neurology, Beijing Rehabilitation Hospital Affiliated to Capital Medical University, Beijing, China.
²⁹ Department of Neurology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
³⁰ Department of Neurology, Henry Ford Hospital, Detroit, MI, USA.
³¹ McGill Centre for Studies in Aging, McGill University, Montreal, Canada. Electronic address: serge.gauthier@mcgill.ca.

PMID: 29433981
DOI: 10.1016/j.jalz.2017.12.006

Abstract

Introduction: The socioeconomic costs of Alzheimer's disease (AD) in China and its impact on global economic burden remain uncertain.

Methods: We collected data from 3098 patients with AD in 81 representative centers across China and estimated AD costs for individual patient and total patients in China in 2015. Based on this data, we re-estimated the worldwide costs of AD.

Results: The annual socioeconomic cost per patient was US $19,144.36, and total costs were US $167.74 billion in 2015. The annual total costs are predicted to reach US $507.49 billion in 2030 and US $1.89 trillion in 2050. Based on our results, the global estimates of costs for dementia were US $957.56 billion in 2015, and will be US $2.54 trillion in 2030, and US $9.12 trillion in 2050, much more than the predictions by the World Alzheimer Report 2015.

Discussion: China bears a heavy burden of AD costs, which greatly change the estimates of AD cost worldwide.

Keywords: Alzheimer's; Cost of illness; Dementia; Observational study.

Publication types

Multicenter Study
Observational Study
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aged, 80 and over
Alzheimer Disease / economics*
Alzheimer Disease / epidemiology
China
Cost of Illness*
Cross-Sectional Studies
Female
Forecasting
Health Care Costs
Humans
Male
Middle Aged
Socioeconomic Factors