Heart Failure Interventions Targeting Impaired Left Ventricles in Structural Heart Disease

Curr Cardiol Rep. 2018 Feb 12;20(2):8. doi: 10.1007/s11886-018-0950-6.

Abstract

Purpose of review: Interventional techniques have been developed for a wide spectrum of mechanisms of heart failure (HF), especially in valvular heart disease and cardiomyopathies (ischaemic cardiomyopathy and hypertrophic cardiomyopathy). In this article, we review recent reports on catheter interventions to treat patients with HF.

Recent findings: Direct modification using the Parachute device and the REVIVENT-TC device for patients with impaired left ventricle with large infarct scars improves geometry and haemodynamic efficiency, resulting in a reduction of HF symptoms. Interatrial shunt therapy improves symptoms and quality of life in HF patients. Uniquely, left ventricular outflow tract obstruction has also been targeted in patients with transcatheter mitral valve implantation. For advanced stage HF patients with prohibitively high surgical risk, emerging transcatheter interventions make it possible to modify life-limiting symptoms. Further results on HF interventions are expected from ongoing clinical trials.

Keywords: Heart failure interventions; Interatrial shunt device; Ischaemic cardiomyopathy; Left ventricular outflow tract obstruction; Left ventricular reconstruction.

Publication types

  • Review

MeSH terms

  • Cardiomyopathy, Hypertrophic / complications
  • Heart Failure / etiology
  • Heart Failure / surgery*
  • Heart Valve Diseases / complications
  • Heart Valve Prosthesis Implantation / methods*
  • Heart Ventricles / surgery*
  • Hemodynamics
  • Humans
  • Mitral Valve / surgery*
  • Myocardial Ischemia / complications
  • Quality of Life
  • Ventricular Dysfunction, Left / complications
  • Ventricular Outflow Obstruction / complications