Cough as the sole manifestation of pericardial effusion

BMJ Case Rep. 2018 Feb 5:2018:bcr2017222327. doi: 10.1136/bcr-2017-222327.

Abstract

A 59-year-old woman with paroxysmal atrial fibrillation (AF) presented with severe non-productive cough, malaise, low-grade fever and AF flare-up 3 weeks following pulmonary vein isolation with radiofrequency catheter ablation. She denied chest pain or dyspnoea. Patient was haemodynamically stable. There was no pulsus paradoxus. Laboratories showed leucocytosis and elevated C-reactive protein. ECG showed sinus tachycardia. CT abdomen and pelvis showed a large pericardial effusion (PE). Shortly after admission, she developed AF with rapid ventricular response, responsive to intravenous amiodarone. Transthoracic echocardiogram revealed 2.4 cm posterior PE without tamponade physiology, non-amenable to pericardiocentesis via sub-xiphoid approach. Patient underwent left thoracoscopic pericardial window with removal of 250 cc bloody fibrinous fluid. Cough improved significantly and she was discharged on oral amiodarone and apixaban. Repeat CT chest after 2 weeks for recurrent cough showed a small PE, treated with oral prednisone for suspected postablation pericarditis, with complete resolution of cough. Amiodarone was stopped without recurrence of AF.

Keywords: arrhythmias; cardiovascular medicine; pacing and electrophysiology; pericardial disease.

Publication types

  • Case Reports

MeSH terms

  • Amiodarone / therapeutic use
  • Anti-Arrhythmia Agents / therapeutic use*
  • Atrial Fibrillation / physiopathology*
  • Atrial Fibrillation / therapy
  • Catheter Ablation / adverse effects*
  • Cough
  • Echocardiography
  • Female
  • Fever
  • Humans
  • Middle Aged
  • Pericardial Effusion / diagnosis*
  • Pericardial Effusion / physiopathology
  • Pericardial Effusion / therapy
  • Pericardial Window Techniques*
  • Pericarditis / drug therapy*
  • Pericarditis / etiology
  • Postoperative Complications
  • Prednisone / therapeutic use*
  • Pyrazoles / therapeutic use
  • Pyridones / therapeutic use
  • Recurrence
  • Treatment Outcome

Substances

  • Anti-Arrhythmia Agents
  • Pyrazoles
  • Pyridones
  • apixaban
  • Amiodarone
  • Prednisone