Can aldosterone break your heart? Takotsubo cardiomyopathy in a patient with newly diagnosed primary aldosteronism

BMJ Case Rep. 2018 Feb 5:2018:bcr2017223472. doi: 10.1136/bcr-2017-223472.

Abstract

We report a case of a 47-year-old Caucasian woman with medical history of hypertension and hypokalemia, who presented to Emergency Room with symptoms resembling acute coronary syndrome ST-segment elevation myocardial infarction. Coronary angiogram revealed clear coronary arteries and left ventriculogram confirmed the diagnosis of Takotsubo cardiomyopathy. She was treated conservatively with good clinical outcome. Subsequent testing revealed underlying primary aldosteronism.

Keywords: adrenal disorders; cardiovascular medicine; endocrinology; heart failure; interventional cardiology.

Publication types

  • Case Reports

MeSH terms

  • Aldosterone / blood*
  • Anti-Arrhythmia Agents / therapeutic use
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Anticholesteremic Agents / therapeutic use
  • Antihypertensive Agents / therapeutic use*
  • Aspirin / therapeutic use
  • Atorvastatin / therapeutic use
  • Chest Pain
  • Coronary Angiography
  • Electrocardiography
  • Female
  • Humans
  • Hyperaldosteronism / complications*
  • Hyperaldosteronism / diagnosis*
  • Hyperaldosteronism / drug therapy
  • Hyperaldosteronism / physiopathology
  • Hypertension
  • Metoprolol / therapeutic use
  • Middle Aged
  • Takotsubo Cardiomyopathy / complications*
  • Takotsubo Cardiomyopathy / diagnosis*
  • Takotsubo Cardiomyopathy / physiopathology
  • Treatment Outcome

Substances

  • Anti-Arrhythmia Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Anticholesteremic Agents
  • Antihypertensive Agents
  • Aldosterone
  • Atorvastatin
  • Metoprolol
  • Aspirin