Covalent modifications of polysaccharides in mycobacteria

Nat Chem Biol. 2018 Feb 14;14(3):193-198. doi: 10.1038/nchembio.2571.

Abstract

Mycobacteria produce carbohydrates of exceptional structures that are covalently modified by unique substituents, whose functional characterization could expand our understanding of how mycobacteria adapt to their environment.

MeSH terms

  • Animals
  • Carbohydrates / chemistry
  • Fatty Acids / chemistry
  • Galactans / chemistry
  • Humans
  • Lipid A / chemistry
  • Lipopolysaccharides / chemistry
  • Mice
  • Mycobacterium / metabolism*
  • Mycobacterium leprae / metabolism
  • Mycobacterium tuberculosis / metabolism
  • Mycobacterium ulcerans / metabolism
  • Peptides / chemistry
  • Polysaccharides / chemistry*

Substances

  • Carbohydrates
  • Fatty Acids
  • Galactans
  • Lipid A
  • Lipopolysaccharides
  • Peptides
  • Polysaccharides
  • lipomannan
  • arabinogalactan