Mechanisms Involved in Glycemic Control Promoted by Exercise in Diabetics

Curr Diabetes Rev. 2019;15(2):105-110. doi: 10.2174/1573399814666180214144717.

Abstract

Introduction: Diabetes mellitus is a metabolic disease characterized by high glycemic levels for long periods. This disease has a high prevalence in the world population, being currently observed an increase in its incidence. This fact is mainly due to the sedentary lifestyle and hypercaloric diets. Non-pharmacological interventions for glycemic control include exercise, which promotes changes in skeletal muscle and adipocytes. Thus, increased glucose uptake by skeletal muscle and decreased insulin resistance through modulating adipocytes are the main factors that improve glycemic control against diabetes.

Conclusion: It was sought to elucidate mechanisms involved in the improvement of glycemic control in diabetics in front of the exercise.

Keywords: Diabetes mellitus; glycemia; insulin; metabolic control; molecular mechanisms; physical activity..

Publication types

  • Review

MeSH terms

  • Blood Glucose / metabolism*
  • Diabetes Mellitus / metabolism
  • Diabetes Mellitus / therapy*
  • Exercise*
  • Humans
  • Hyperglycemia / metabolism
  • Hyperglycemia / therapy
  • Insulin / metabolism*
  • Muscle, Skeletal / metabolism*
  • Sedentary Behavior

Substances

  • Blood Glucose
  • Insulin