Autophagy: Suicide Prevention Hotline for the Gut Epithelium

Mayara Grizotte-Lake; Shipra Vaishnava

doi:10.1016/j.chom.2018.01.015

Autophagy: Suicide Prevention Hotline for the Gut Epithelium

Cell Host Microbe. 2018 Feb 14;23(2):147-148. doi: 10.1016/j.chom.2018.01.015.

Authors

Mayara Grizotte-Lake¹, Shipra Vaishnava²

Affiliations

¹ Molecular Microbiology and Immunology, Brown University, Providence, RI 02912, USA.
² Molecular Microbiology and Immunology, Brown University, Providence, RI 02912, USA. Electronic address: shipra_vaishnava@brown.edu.

PMID: 29447690
DOI: 10.1016/j.chom.2018.01.015

Abstract

Autophagy is genetically associated with inflammatory bowel disease (IBD); however, its role remains unclear in disease pathogenesis. Three recent studies reveal a novel cytoprotective role of autophagy during viral, bacterial, and protozoan-triggered IBD (Burger et al., 2018; Matsuzawa-Ishimoto et al., 2017; Pott et al., 2018).

Publication types

Comment

MeSH terms

Autophagy*
Hotlines*
Humans
Inflammatory Bowel Diseases / microbiology
Suicide