Persistent candidemia despite appropriate fungal therapy: First case of Candida auris from the United Arab Emirates

Int J Infect Dis. 2018 May:70:36-37. doi: 10.1016/j.ijid.2018.02.005. Epub 2018 Feb 13.

Abstract

In this case, we report an elderly patient with multiple chronic conditions and prolonged intensive care unit (ICU) stays who had recurrent Candida auris (C. auris) in blood despite antifungal therapy. C. auris was misidentified using conventional automated identification system as Candida haemulonii resulting in delayed diagnosis. The isolate showed increasing minimum inhibitory concentrations (MICs) to different antifungal drugs and persisted in the patient's blood before the patient deceased. This is the first case of C. auris reported from the United Arab Emirates (UAE); laboratories should be aware of this Candida species and should confirm suspected cases since it is an emerging multi-drug resistant and health-care associated Candida.

Keywords: Candida auris; Healthcare- associated; Multidrug resistant.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Antifungal Agents / administration & dosage*
  • Antifungal Agents / adverse effects
  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use*
  • Candida / isolation & purification*
  • Candidemia / drug therapy*
  • Candidemia / microbiology*
  • Candidiasis / blood
  • Candidiasis / drug therapy*
  • Candidiasis / microbiology*
  • Diagnostic Errors
  • Drug Resistance, Fungal / drug effects*
  • Female
  • Humans
  • Microbial Sensitivity Tests
  • Species Specificity
  • United Arab Emirates

Substances

  • Antifungal Agents