Brachial plexitis or neuritis? MRI features of lesion distribution in Parsonage-Turner syndrome

Muscle Nerve. 2018 Sep;58(3):359-366. doi: 10.1002/mus.26108. Epub 2018 Mar 25.

Abstract

Introduction: This study seeks to characterize lesion distribution in Parsonage-Turner Syndrome (PTS) using high-resolution MRI.

Methods: MRIs of 27 patients with clinically confirmed PTS were reviewed. Two radiologists independently evaluated the brachial plexus proper, side and terminal plexus branches, and more distal, upper extremity nerves.

Results: All patients had at least 1 clinically involved nerve. MRI revealed that the plexus appeared normal in 24 of 27 patients; in 3 other patients, signal hyperintensity was seen immediately proximal to the take-off of abnormal side or terminal branch nerves. Focal intrinsic constrictions were detected in 32 of 38 nerves. MRI interobserver agreement was high (Cohen's κ = 0.839).

Discussion: MRI findings, corroborated by electrodiagnostic testing, localized abnormalities to plexus branches and peripheral nerves, suggesting that PTS is characterized by 1 or more mononeuropathies rather than changes involving a portion of or the complete plexus proper. These results may improve diagnosis, prognostication, and management. Muscle Nerve 58: 359-366, 2018.

Keywords: Parsonage-Turner syndrome; brachial neuritis; brachial plexitis; hourglass constrictions; mononeuropathy multiplex; neuralgic amyotrophy.

MeSH terms

  • Adult
  • Brachial Plexus / diagnostic imaging*
  • Brachial Plexus / physiopathology*
  • Brachial Plexus Neuritis / diagnostic imaging*
  • Brachial Plexus Neuritis / physiopathology*
  • Electrodiagnosis / methods
  • Electromyography / methods
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Retrospective Studies