Diagnosis and Management of VTE in Pregnancy

Clin Obstet Gynecol. 2018 Jun;61(2):206-218. doi: 10.1097/GRF.0000000000000354.

Abstract

Venous thromboembolism is a leading cause of maternal death. Because of the low absolute frequency of events, however, outcome-based clinical data are limited. Consequently, clinicians must additionally rely both on published guidelines and on extrapolation of data from studies focused on nonpregnant individuals. The diagnosis and treatment of deep vein thrombosis, pulmonary embolism, and cerebral vein and dural sinus thrombosis are complicated by pregnancy, and often require modifications to standard diagnostic and treatment algorithms outside of pregnancy. Treatment of VTE in pregnant women is in particular need of future research.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Anticoagulants / administration & dosage
  • Anticoagulants / adverse effects
  • Delivery, Obstetric
  • Diagnostic Imaging
  • Drug Administration Schedule
  • Female
  • Humans
  • Intracranial Thrombosis / diagnosis
  • Intracranial Thrombosis / drug therapy
  • Labor, Obstetric
  • Patient Care Team
  • Pregnancy
  • Pregnancy Complications, Hematologic / diagnosis*
  • Pregnancy Complications, Hematologic / drug therapy*
  • Pulmonary Embolism / diagnosis
  • Pulmonary Embolism / drug therapy
  • Stroke / prevention & control
  • Venous Thromboembolism / diagnosis*
  • Venous Thromboembolism / drug therapy*
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / drug therapy

Substances

  • Anticoagulants