Adipose and Hair Function: An aPPARent Connection

Nasif Islam; Luis A Garza

doi:10.1016/j.jid.2017.10.019

Adipose and Hair Function: An aPPARent Connection

J Invest Dermatol. 2018 Mar;138(3):480-482. doi: 10.1016/j.jid.2017.10.019.

Authors

Nasif Islam¹, Luis A Garza²

Affiliations

¹ Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
² Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address: LAG@jhmi.edu.

Abstract

Adipose tissue plays essential roles in various aspects of skin physiology, from regulating hair follicle morphogenesis to wound healing. Peroxisome proliferator-activated receptor gamma is important for the maintenance of adipose tissue and has been implicated in some types of hair loss; however, its function during the hair cycle is still unclear. Sardella et al. investigate the role of peroxisome proliferator-activated receptor gamma in hair follicle morphogenesis using a novel global peroxisome proliferator-activated receptor gamma-null mouse.

Publication types

Comment

MeSH terms

Adiposity
Animals
Hair Follicle*
Mice
Morphogenesis
PPAR gamma*
Skin Physiological Phenomena

Substances

PPAR gamma

Abstract

Publication types

MeSH terms

Substances

Grants and funding