Adipose and Hair Function: An aPPARent Connection

J Invest Dermatol. 2018 Mar;138(3):480-482. doi: 10.1016/j.jid.2017.10.019.


Adipose tissue plays essential roles in various aspects of skin physiology, from regulating hair follicle morphogenesis to wound healing. Peroxisome proliferator-activated receptor gamma is important for the maintenance of adipose tissue and has been implicated in some types of hair loss; however, its function during the hair cycle is still unclear. Sardella et al. investigate the role of peroxisome proliferator-activated receptor gamma in hair follicle morphogenesis using a novel global peroxisome proliferator-activated receptor gamma-null mouse.

Publication types

  • Comment

MeSH terms

  • Adiposity
  • Animals
  • Hair Follicle*
  • Mice
  • Morphogenesis
  • PPAR gamma*
  • Skin Physiological Phenomena


  • PPAR gamma