Update on Standard Operating Procedures in Preclinical Research for DMD and SMA Report of TREAT-NMD Alliance Workshop, Schiphol Airport, 26 April 2015, The Netherlands

J Neuromuscul Dis. 2018;5(1):29-34. doi: 10.3233/JND-170288.

Abstract

A workshop took place in 2015 to follow up TREAT-NMD activities dedicated to improving quality in the preclinical phase of drug development for neuromuscular diseases. In particular, this workshop adressed necessary future steps regarding common standard experimental protocols and the issue of improving the translatability of preclinical efficacy studies.

Keywords: DMD; SMA; preclinical; standard operating procedures; translational research.

Publication types

  • Congress

MeSH terms

  • Animals
  • Biomedical Research
  • Disease Models, Animal
  • Drug Discovery
  • Education
  • Humans
  • Muscular Atrophy, Spinal / drug therapy*
  • Muscular Dystrophy, Duchenne / drug therapy*
  • Netherlands
  • Outcome Assessment, Health Care
  • Quality Improvement*
  • Translational Medical Research*