Amiodarone is a frequently prescribed anti-arrhythmic medication. Amiodarone is approved by the U.S. Food and Drug Administration (FDA) specifically for the treatment of life-threatening ventricular arrhythmias. However, this drug is also widely used off-label to treat supraventricular tachyarrhythmias, such as atrial fibrillation, and to prevent ventricular tachyarrhythmias in high-risk patients. This activity comprehensively reviews amiodarone's indications, mechanisms of action, contraindications, and adverse events profile in the clinical setting. These insights are crucial for the collaborative efforts of an interprofessional healthcare team responsible for caring for patients with arrhythmia.
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