Amphotericin B

Book
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.
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Excerpt

Amphotericin B deoxycholate, an esteemed member of the polyene class of antifungals, has been a cornerstone in therapy against invasive fungal infections for over 5 decades. This drug has witnessed significant advancements by introducing novel lipid formulations that exhibit a reduced nephrotoxic profile compared to the traditional formulation. This comprehensive activity is designed to meticulously elucidate the indications, contraindications, pharmacological activity, adverse events, and toxicity associated with amphotericin B, equipping members of the interprofessional healthcare team with essential insights for adeptly managing mycotic infections in diverse clinical settings. Participants gain a profound understanding of the antifungal applications of amphotericin B, empowering them to contribute effectively to the collaborative care of patients grappling with fungal infections.

Publication types

  • Study Guide