Amphotericin B

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan.


Amphotericin B deoxycholate belongs to the polyene class of antifungals. It is also known by the conventional name amphotericin B and has been used for the treatment of invasive fungal infections for more than 50 years. Newer lipid formulations that are less nephrotoxic as compared with conventional amphotericin B are available. This activity reviews the indications, contraindications, activity, adverse events, toxicity, and other key elements of antifungal uses of amphotericin B in the clinical setting as relates to the essential points needed by members of an interprofessional team managing the care of patients who present with mycotic infections.

Publication types

  • Study Guide